Cluster of Excellence Precision Medicine in Chronic Inflammation (PMI)

The Rise of Chronic Inflammatory Diseases An increasing number of people in industrialized nations suffer from chronic inflammatory diseases, such as Crohn’s disease, psoriasis, diabetes, or rheumatism. These conditions severely impact the quality of life for millions of individuals.

Nearly 20 Years we are shaping the medicine of tomorrow with the Cluster of Excellence "Precision Medicine in Chronic Inflammation" (PMI). Supported by the Excellence Strategy of the German Federal and State Governments, we bridge the gap between clinical practice and fundamental research at the highest international level.

From Bench to Bedside Our focus is on precision medicine. We ensure that scientific breakthroughs translate directly into patient care without delay—aiming for better diagnosis, more precise therapies, and effective prevention.

Cluster news

22.07.2026
[EN]

Vitamin B3 for the gut: From basic discovery to clinical translation

Innovation Transfer Award recognizes a long-standing collaboration between researchers at University Medical Center Schleswig-Holstein (UKSH), the Cluster of Excellence Precision Medicine in Chronic Inflammation(PMI), and CONARIS Research Institute AG.

 

 
22.07.2026
Humane Makrophagen

Asthma: New Mechanism of Action Curbs Inflammatory Response

A team from the University of Bonn and the Research Center Borstel, Leibniz Lung Center (FZB) has discovered a previously unknown mechanism of action for a synthetic peptide that mitigates excessive inflammatory responses in allergic asthma. This mechanism specifically inhibits a key inflammatory switch in the immune system and opens up new avenues for treating chronic inflammatory diseases. The…

 
16.07.2026
[EN]

Testosterone therapy without documented evidence of deficiency associated with higher long-term cardiovascular risk

Lübeck / Frankfurt / Stockholm / Liverpool / Safed, 9 July 2026 — An international study published in eBioMedicine shows that testosterone therapy in the absence of a documented testosterone deficiency is associated with a long-term increased risk of serious cardiovascular disease and higher mortality. The analysis is based on health data from more than 350,000 men.

 

 
14.07.2026
[EN]

From clinical evidence to mechanism: Blood cover study on intravenous iron and fracture risk

An international translational study involving IKMB researchers combines patient-level evidence with experimental biology and highlights why the choice of intravenous iron formulation matters.

 

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