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RTF X: General Patient Access and CCIM
Coordinators: A. Franke (CAU), B. Hoyer (CCIM, CAU), G. Riemekasten (UzL), S. Schreiber (CAU), D. Thaci (CCIM, UzL), S. Weidinger (CAU)
The research area RTF X facilitates access to patients with chronic inflammatory skin, joint and/or intestinal diseases. They receive interdisciplinary care at the Comprehensive Center for Inflammation Medicine (CCIM), with the goal of early detection of diseases in other organs and identification of correlations in order to achieve optimal success in treatment. At the same time, the clinical data gained and the samples collected (e.g. blood or genetic material) provides a better understanding of the disease.
What does this research area's work build on?
The Comprehensive Centers for Inflammation Medicine (CCIMs) have excellent networks and are ideally positioned on an interdisciplinary basis. Case conferences, joint consultation hours, clinical studies and own research projects ensure that the patients benefit from the latest findings in fundamental research and clinical research, as well as innovative treatments. The documentation of the manifestations (phenotypes) of the disease, and the infrastructure for recording, processing and evaluating this data and analyzing the biological samples has already been established.
What are the main research objectives?
The primary goal is to discover potential biomarkers, which enables clinicians to predict the treatment success or typical comorbidities for the individual patients, to optimize the costs of the treatment, and to make better individualized treatment decisions.
What makes this research area special?
The unique features of the research area include the special access to the patients investigated, with the large number of doctors assigned and the long-term relationship with the CCIMs, which makes long-term observations possible at all, combined with the collection of high-quality clinical data and the findings from laboratory studies.
What does this research area contribute to Precision Medicine in Chronic Inflammation?
The members are searching for customized treatments with the earliest possible diagnosis. While doing so, they also maintain a special focus on comorbidities. The data they gain and the samples they collect enables them to facilitate efforts in other research areas, e.g. work on genetic risk profiles (RTF I), investigations of the microbiome (RTF II), possible output parameters (RTF VI) or research on non-genetic factors (nutrition, RTF V).
Cooperation with other research areas in the cluster
In RTF X there are close links between dermatology, rheumatology and gastroenterology. In addition, they collaborate with the various biobanks, the Centre for Clinical Studies (ZKS) and research areas RTF I-VII and RTF IX.
Members
Prof. Dr. Claudia Bozzaro
Associated member
UKSH Campus Kiel
Institute of Experimental Medicine
Biomedical Ethics
Universität Münster
Institute for Ethics, History and Theory of Medicine
Prof. Dr. rer. nat. Andre Franke
Full member
Kiel University
Institute of Clinical Molecular Biology
Genetics & Bioinformatics
Dr. Jeanette Franzenburg
Associated member
Kiel University
Institute of Clinical Molecular Biology
AG Prof. Franke
Prof. Dr. Mathieu Groussin
Full member
Kiel University
Institute of Clinical Molecular Biology
Prof. Dr. Jan Heyckendorf
Full member
UKSH Campus Kiel
Department of Internal Medicine I
Leibniz Lungenklinik
Prof. Dr. rer. nat. Ben Krause-Kyora
Full member
Kiel University
Institute of Clinical Molecular Biology
Ancient DNA Research
Prof. Dr. med. Wolfgang Lieb
Full member
Kiel University
Institute of Epidemiology
Prof. Dr. Klaus F. Rabe
Full member
LungenClinic Grosshansdorf
Section Pneumology
Prof. Dr. med. Stefan Schreiber
Spokesperson
Kiel University
Institute of Clinical Molecular Biology
Prof. Dr. Markus Weckmann
Full member
Research Center Borstel - Leibniz Lung Center
Epigenetics of Chronic Lung Diseases
Priority Research Area Chronic Lung Diseases
Prof. Dr. Stephan Weidinger
Full member
UKSH Campus Kiel
Department of Dermatology, Venereology and Allergology