Review: COVID-19 host genetics and ABO blood group susceptibility

What is the role of ABO blood group in SARS-CoV-2 infection and/or severe COVID-19, and what genetic risk factors are known to date?

In a review article, Prof. David Ellinghaus, bioinformatician at the Institute for Clinical Molecularbiology (IKMB) of Kiel University, summarizes recent genetic findings and data from secondary infection rates in couples and modeling experiments to explain the influence of ABO blood groups on SARS-CoV-2 transmission and infection rates within a population.

For a brief summary, watch this one-minute video (© Cambridge University Press):



Growing evidence links risk of COVID-19 infection to blood type


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portrait photo
© S. Klahn, Cluster of Excellence PMI, Uni Kiel

Prof. Dr. David Ellinghaus, member of the Cluster of Excellence „Precision Medicine in Chronic Inflammation“ and Professor at the institute of Clinical Molecular Biology, CAU and UKSH, Campus Kiel.

Original publication:

Ellinghaus D (2023). COVID-19 host genetics and ABO blood group susceptibility. Cambridge Prisms: Precision Medicine, 1, e10, 1–12